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Why did fluid resuscitation increase mortality in African children with shock in the FEAST trial?

Detailed analysis of data from the FEAST trial has revealed that the higher rates of death among children given rapid fluid resuscitation seem to be because of cardiovascular collapse rather than fluid overload. Fluid resuscitation increased death rates in all subgroups (the symptoms the children had, whether or not they had anaemia, and which definition of shock was used). These results question the speed & volume of fluids used for treating children in shock due to infections in Africa. Read more

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News archive

Displaying results 1-10 of 98. Page 1 of 10.

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• Why did fluid resuscitation increase mortality in African children with shock in the FEAST trial?
  11 May 2012
• Routine laboratory monitoring of people on antiretroviral therapy for HIV is not cost-effective
  04 May 2012
• MRC CTU now on Twitter
  04 May 2012
• General practice research unit to close
  29 March 2012
• Involving patients and the public can benefit clinical research
  27 March 2012
• Innovative trial finds celecoxib does not improve prostate cancer outcomes
  26 March 2012
• DOMINO trial results show donepezil is associated with cognitive benefits for Alzheimer’s patients
  16 March 2012
• MRC Clinical Trials Unit on World Tuberculosis Day 2012
  14 March 2012
• Treating infants with HIV early, and then interrupting their treatment, leads to better results than deferring treatment
  07 March 2012
• START reaches recruitment halfway point
  10 February 2012

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